Implications for human adipose‐derived stem cells in plastic surgery

Journal of Cellular and Molecular Medicine

Derek A. Banyard¹  Ara A. Salibian¹  Alan D. Widgerow¹ 

[1] Department of Plastic Surgery, University of California, Irvine, Orange, CA, USA

关键词: stem cell;    mesenchymal stem cell;    adipose‐derived stem cell;    lipotransfer;   

DOI  :  10.1111/jcmm.12425

来源: Wiley

【 摘 要 】

Abstract

Adipose-derived stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs) that possess many of the same regenerative properties as other MSCs. However, the ubiquitous presence of ADSCs and their ease of access in human tissue have led to a burgeoning field of research. The plastic surgeon is uniquely positioned to harness this technology because of the relative frequency in which they perform procedures such as liposuction and autologous fat grafting. This review examines the current landscape of ADSC isolation and identification, summarizes the current applications of ADSCs in the field of plastic surgery, discusses the risks associated with their use, current barriers to universal clinical translatability, and surveys the latest research which may help to overcome these obstacles.

【 授权许可】

CC BY   
© 2014 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.