Case series of rash associated with influenza B in school children

Influenza and Other Respiratory Viruses

Danuta M. Skowronski³  Catharine Chambers³  William Osei²  Jill Walker²  Martin Petric³  Monika Naus³  Yan Li¹ 

[1] National Microbiology Laboratory, Winnipeg, MB, Canada;Northern Health Authority, Prince George, BC, Canada;British Columbia Centre for Disease Control, Vancouver, BC, Canada

关键词: Exanthem;    inactivated;    influenza;    influenza vaccine;    influenza‐like illness;    morbilliform;    rash;    vaccine;   

DOI  :  10.1111/irv.12296

来源: Wiley

【 摘 要 】

Abstract

This case series describes morbilliform and other rash presentations among schoolchildren during a March 2014 outbreak of influenza-like illness (ILI) in British Columbia, Canada. Multiplex nucleic acid testing of nasopharyngeal specimens and paired serologic investigations identified that influenza B, characterized as B/Massachusetts/02/2012-like (Yamagata-lineage), was the only viral aetiology and most likely cause of ILI and rash. An association between influenza B and rash has been described infrequently elsewhere, and not previously in North America. Influenza B should be considered in the differential diagnosis of febrile exanthem. Evaluation of the nature, incidence and contributing agent–host–environment interactions, and immunologic mechanisms to possibly explain influenza-associated rash is warranted.

【 授权许可】

CC BY   
© 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.