The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak

EMBO Molecular Medicine

Helge Karch⁶  Erick Denamur²  Ulrich Dobrindt⁶  B. Brett Finlay⁴  Regine Hengge⁵  Ludgers Johannes¹  Eliora Z. Ron⁷  Tone Tønjum³  Philippe J. Sansonetti⁸ 

[1] Traffic, Signaling, and Delivery Laboratory, UMR144 Curie/CNRS, Curie Institute, Paris, France;INSERM, Université Paris Diderot, UMR-S 722, Paris, France;Center for Molecular Biology and Neuroscience, Institute of Microbiology, University of Oslo, Oslo, Norway;Michael Smith Laboratories, Department of Microbiology and Immunology, The University of British Columbia, Vancouver, British Columbia, Canada;Institut für Biologie – Mikrobiologie, Freie Universität Berlin, Berlin, Germany;Institute of Hygiene, University Münster, Münster, Germany;Faculty of Life Sciences, Department of Molecular Microbiology and Biotechnology, MIGAL Galil Research Center, Tel Aviv University, Israel;Unité de Pathogénie Microbienne Moléculaire et Unité INSERM 786, Institut Pasteur, Paris, France

关键词: Escherichia coli;    HUS;    infection;    O104:H4;    outbreak;   

DOI  :  10.1002/emmm.201201662

来源: Wiley

【 摘 要 】

Abstract

In response to the 2011 European health alert caused by a pathogenic Escherichia coli O104:H4 outbreak, the European Academy of Microbiology (EAM), established by the Federation of European Microbiological Societies (FEMS), convened a meeting in Paris on November 30th, 2011 on ‘EHEC infection and control’ attended by world renowned experts in pathogenic E. coli. The major aims of this group were to review the scientific issues raised by the outbreak, to assess the handling of the crisis at the scientific and political levels, and to propose future actions. Several conclusions, which will have impact on future potential E. coli outbreaks, are outlined here.

【 授权许可】

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Copyright © 2012 EMBO Molecular Medicine

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