A Comparative Review of Vitamin E and Associated Equine Disorders

Journal of Veterinary Internal Medicine

C.J. Finno¹ 

[1] Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN

关键词: Genetics;    Neurology;    Neuromuscular disorders;    Nutrition;    Spinal cord disease;   

DOI  :  10.1111/j.1939-1676.2012.00994.x

来源: Wiley

【 摘 要 】

Abstract

Vitamin E is a primary chain-breaking antioxidant that prevents cyclic propagation of lipid peroxidation. Across species, vitamin E is essential for normal neuromuscular function by acting as a potent antioxidant, as well as by modulating the expression of certain genes, inhibiting platelet aggregation and stabilizing plasma membranes. This review focuses on vitamin E structure, absorption, metabolism, current equine dietary recommendations, the interplay between antioxidants and exercise, a discussion of the necessity of vitamin E supplementation in the horse above the Nutritional Research Council (NRC) 2007 requirements, and a review of equine diseases that are associated with a vitamin E deficiency. Particular emphasis is placed on the proteins involved in vitamin E absorption, transport, and metabolism as potential candidates for vitamin E-associated diseases across species.

【 授权许可】

Unknown   
Copyright © 2012 by the American College of Veterinary Internal Medicine