Proton‐based chemoradiation for synchronous bilateral non‐small‐cell lung cancers: A case report

Thoracic Cancer

Wenyin Shi¹  Romaine C. Nichols, Jr²  Stella Flampouri²  Zuofeng Li²  Wen Hsi²  Soon Huh²  Meng Wei Ho²  Randall H. Henderson²  Nancy P. Mendenhall¹ 

[1] Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA;University of Florida, Proton Therapy Institute, Jacksonville, FL, USA

关键词: Case report;    chemotherapy;    lung cancer;    proton therapy;    radiation therapy;   

DOI  :  10.1111/j.1759-7714.2012.00141.x

来源: Wiley

【 摘 要 】

Abstract

In this case report, we present the history and treatment of a 70-year-old man with synchronous bilateral non-small-cell lung cancers with proton-beam radiation. Surgical treatment was not feasible and optimized photon intensity-modulated radiotherapy (IMRT) to the primary tumors would have resulted in unacceptably high normal-tissue exposures. Proton-beam radiation enabled radiation dose escalation and concurrent chemotherapy while maintaining normal-tissue tolerance.

【 授权许可】

Unknown   
© 2012 Tianjin Lung Cancer Institute and Wiley Publishing Asia Pty Ltd