Reticular activating system of a central pattern generator: premovement electrical potentials

Physiological Reports

Jesus A. Tapia¹  Argelia Trejo¹  Pablo Linares¹  J. Manuel Alva¹  Rumyana Kristeva² 

[1] Institute of Physiology, Benemérita Universidad Autónoma de Puebla, Puebla, Puebla, México;Neurological Clinic, University of Freiburg, Freiburg, Germany

关键词: Dorsal horn neurons;    locomotion;    scratch reflex;    scratching;    slow oscillations;    spinal rehabilitation;   

DOI  :  10.1002/phy2.129

来源: Wiley

【 摘 要 】

Abstract

For the first time, here we characterize a bulbar reticular activating system (RAS) of neurons in decerebrate, deafferented and decerebellated cats producing a premovement electrical potential that we named obex slow potential (OSP). The OSP occurs about 0.8 ± 0.4 sec prior to the onset of a fictive-scratching-episode. Here, we describe two classes of bulbar neurons, off-on, which are silent but exhibit a 80 ± 56 Hz firing discharge at the beginning of (and during) the OSP, and on-off interneurons, with a 27 ± 14 Hz firing activity that stops at the beginning of (and during) the OSP. We suggest that these OSP-associated neurons belong to a descending RAS, which contributes to the activation of the spinal central pattern generators.

【 授权许可】

CC BY   
© 2013 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

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