Treatment of chronic lymphocytic leukemia with bendamustine in an HIV‐infected patient on antiretroviral therapy: a case report and review of the literature

Clinical Case Reports

Naoki Shimada²  Koichiro Yuji¹  Nobuhiro Ohno¹  Tomohiko Koibuchi⁴  Naoki Oyaizu³  Kaoru Uchimaru¹ 

[1] Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan;Promotion Plan for the Platform of Human Resource Development for Cancer, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan;Department of Laboratory Medicine, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan;Department of Infectious Diseases and Applied Immunology, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

关键词: Bendamustine;    chronic lymphocytic leukemia;    HIV;    small lymphocytic lymphoma;   

DOI  :  10.1002/ccr3.244

来源: Wiley

【 摘 要 】

Key Clinical Message

Few reports have described the coincidence of chronic lymphocytic leukemia (CLL) and HIV. We administered bendamustine to an HIV-positive refractory CLL patient and obtained a significant objective response. Our results indicate that bendamustine can be used in HIV-infected CLL patients. We also reviewed 12 cases of CLL with HIV infection.

【 授权许可】

CC BY-NC   
© 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

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