Biosensing: Densely Packed Microgoblet Laser Pairs for Cross‐Referenced Biomolecular Detection (Adv. Sci. 10/2015)

Advanced Science

Uwe Bog²  Falko Brinkmann²  Sentayehu Fetene Wondimu³  Tobias Wienhold³  Sarah Kraemmer¹  Christian Koos³  Heinz Kalt¹  Michael Hirtz²  Harald Fuchs²  Sebastian Koeber³ 

[1] Institute of Applied Physics (APH), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany;Institute of Nanotechnology Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany;Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany

关键词: aligned microcontact stamping;    biosensing;    microlasers;    multiplexed surface functionalization;    whispering gallery mode resonators;   

DOI  :  10.1002/advs.201570042

来源: Wiley

【 摘 要 】

Abstract

In article 1500066, U. Bog, M. Hirtz, and co-workers demonstrate on-chip biomolecular sensing using whispering-gallery-mode microgoblet lasers. Biomolecular detection is usually affected by signal disturbances, induced by refractive index and temperature fluctuations inside the liquid analyte. The densely packed laser pairs enable mutual and localized filtering of such signal disturbances. The sensor functionalization is performed by aligned microcontact stamping, resulting in a highly localized, cross-contamination-free treatment of the individual microlasers.

【 授权许可】

CC BY-NC   
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.