Densely Packed Microgoblet Laser Pairs for Cross‐Referenced Biomolecular Detection

Advanced Science

Uwe Bog²  Falko Brinkmann²  Sentayehu Fetene Wondimu³  Tobias Wienhold³  Sarah Kraemmer¹  Christian Koos³  Heinz Kalt¹  Michael Hirtz²  Harald Fuchs²  Sebastian Koeber³ 

[1] Institute of Applied Physics (APH), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany;Institute of Nanotechnology Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany;Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany

关键词: aligned microcontact stamping;    biosensing;    microlasers;    multiplexed surface functionalization;    whispering gallery mode resonators;   

DOI  :  10.1002/advs.201500066

来源: Wiley

【 摘 要 】

Abstract

Microgoblet laser pairs are presented for cross-referenced on-chip biomolecular sensing. Parallel readout of the micro­lasers facilitates effective mutual filtering of highly localized refractive index and temperature fluctuations in the analyte. Cross-referenced detection of two different types of proteins and complete chemical transducer reconfiguration is demonstrated. Selective surface functionalization of the individual lasers with high spatial accuracy is achieved by aligned microcontact stamping.

【 授权许可】

CC BY   
© 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.