A Two‐Photon Excitation Based Fluorogenic Probe for Sialome Imaging in Living Systems

Advanced Science

Lei Rong¹  Chi Zhang¹  Qi Lei¹  Si-Yong Qin¹  Jun Feng¹ 

[1] Key Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan, P.R. China

关键词: click reaction;    fluorescence labeling;    glycoengineering;    zebrafish;   

DOI  :  10.1002/advs.201500211

来源: Wiley

【 摘 要 】

Abstract

Taking advantage of the fluorescence property of alkyne-modified naphthalimide, the two-photon excited fluorogenic probe Naph-yne is used for azide-tagged mannosyl glycoprotein imaging both at the cellular level and for vertebrate model organisms.

【 授权许可】

CC BY   
© 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.