Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals

Frontiers in Public Health

Wei Jiang¹  Lu Zhang¹  Guangru Li²  Weiqiang Chen²  Qiang Li² 

[1] Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China;Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China;College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China;Key Laboratory of Heavy Ion Beam Radiation Biomedicine, Chinese Academy of Sciences, Lanzhou, China;Gansu Provincial Key Laboratory of Heavy Ion Beam Radiation Medical Application, Lanzhou, China;

关键词: accelerator-based BNCT;    beam shaping assembly;    thermal neutron;    epithermal neutron;    multi-terminal;   

DOI  :  10.3389/fpubh.2021.642561

来源: Frontiers

【 摘 要 】

To moderate fast neutrons produced by accelerator to appropriate therapeutic energies for boron neutron capture therapy (BNCT), beam shaping assembly (BSA) is required definitely. In this work, based on a model of 2.5 MeV/30 mA proton accelerator, the Monte Carlo simulation software MCNPX was employed to design multi-terminal BSAs. All parameters for both the thermal and epithermal neutron beams at the exit ports of the designed BSAs meet the treatment recommendation values proposed by the International Atomic Energy Agency (IAEA). The clinical parameters of the thermal and epithermal neutron beams were also calculated for clinical indication consideration.

【 授权许可】

CC BY