Case Report: Early Breast Cancer Recurrence Mimicking BIA-ALCL in a Patient With Multiple Breast Procedures

Frontiers in Surgery

Erika Giacobbi¹  Francesca Servadei¹  Lucia Anemona¹  Francesca Santori²  Marco Pellicciaro²  Gianluca Vanni²  Oreste Claudio Buonomo²  Camilla Di Pasquali²  Marco Materazzo²  Maria Cotesta²  Adriano De Majo²  Andrea Farinaccio³  Tommaso Perretta⁴  Marcello Chiocchi⁴  Rosaria Meucci⁴  Chiara Adriana Pistolese⁴  Federico Tacconi⁵  Amir Sadri⁶  Valentina Bruno⁷ 

[1] Anatomic Pathology, Department of Experimental Medicine, Policlinico Tor Vergata University, Rome, Italy;Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy;Department of Cardiothoracic Anesthesia, Tor Vergata University Hospital, Rome, Italy;Department of Diagnostic Imaging and Interventional Radiology, Molecular Imaging and Radiotherapy, Policlinico Tor Vergata University, Rome, Italy;Division of Thoracic Surgery, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy;Plastic Surgery, Great Hormond Hospital for Children NHS Foundation Trust, London, United Kingdom;Section of Gynecology and Obstetrics, Academic Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy;

关键词: breast implant associated-anaplastic large cell lymphoma;    breast cancer;    locoregional recurrence;    macro textured breast implants;    residual breast tissue;    case report;    breast seroma;    immediate breast reconstruction;   

DOI  :  10.3389/fsurg.2021.606864

来源: Frontiers

【 摘 要 】

Breast reconstruction plays a fundamental role in the therapeutic process of breast cancer treatment and breast implants represents the leading breast reconstruction strategy. Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL), locoregional recurrence in the skin flap, and skin flap necrosis are well-known complications following mastectomy and immediate breast reconstruction (IBR). We report a case of locoregional cancer recurrence in the mastectomy flap mimicking BIA-ALCL, in a patient who underwent 6 breast procedures in four facilities across 15 years including immediate breast reconstruction with macrotextured breast implants. Despite the rate and onset of the disease, clinicians should be aware of BIA-ALCL. Due to the risk of false negative results of fine needle aspiration, clinical suspicion of BIA-ALCL should drive clinicians' choices, aside from cytological results. In the present case, surgical capsulectomy of the abnormal periprosthesic tissue revealed locoregional recurrence.

【 授权许可】

CC BY