Role and Mechanism of Gut Microbiota in Human Disease

Frontiers in Cellular and Infection Microbiology

Li Wang¹  Jinghua Zhou²  Yinwei Chen³ 

[1] Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;Department of Evolutionary Studies of Biosystems, School of Advanced Sciences, Graduate University for Advanced Studies (SOKENDAI), Hayama, Japan;Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;School of Medicine, Zhejiang University, Hangzhou, China;School of Medicine, Hangzhou Normal University, Hangzhou, China;

关键词: gut microbiota;    neurodegenerative diseases;    cardiovascular diseases;    metabolic diseases;    gastrointestinal diseases;   

DOI  :  10.3389/fcimb.2021.625913

来源: Frontiers

【 摘 要 】

The human gut microbiome is a huge microbial community that plays an irreplaceable role in human life. With the further development of research, the influence of intestinal flora on human diseases has been gradually excavated. Gut microbiota (GM) dysbiosis has adverse health effects on the human body that will lead to a variety of chronic diseases. The underlying mechanisms of GM on human diseases are incredibly complicated. This review focuses on the regulation and mechanism of GM on neurodegenerative diseases, cardiovascular diseases, metabolic diseases and gastrointestinal diseases, thus providing a potential target for the prevention and treatment of disease.

【 授权许可】

CC BY