Magnetocardiography for identification of coronary ischemia in patients with chest pain and normal resting 12-lead electrocardiogram

Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

article

Raja Ramesh¹  Sengottuvel Senthilnathan²  Santhosh Satheesh¹  Pragyna Parimita Swain²  Rajesh Patel MTech²  Ajith Ananthakrishna Pillai¹  Gireesan Katholil²  Raja J. Selvaraj¹ 

[1] Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research;Magnetoencephalography Laboratory, SQUIDs and Applications Section, Materials Science Group, Indira Gandhi Centre for Atomic Research

关键词: basic;    clinical;    electrocardiography;    non-invasive techniques;   

DOI  :  10.1111/anec.12715

来源: Wiley

【 摘 要 】

Background Identification of coronary ischemia in patients presenting with chronic chest pain is difficult as resting ECG can be normal. Diagnosis of coronary ischemia requires evaluation during exercise or pharmacological stress. A noninvasive test to identify coronary ischemia at rest without the need for exercise is desirable. We studied the diagnostic accuracy of magnetocardiography (MCG) at rest to detect coronary ischemia in these patients. Methods Patients with chronic chest pain and suspected coronary ischemia with a normal ECG were included. Patients underwent treadmill test (TMT) and were divided into TMT positive and TMT negative groups. MCG was recorded in a magnetically shielded room. Iso-field contour maps generated at the T-wave peak were compared between the groups. From the magnetic field map (MFM), the magnetic field angle at T-wave peak was calculated and was also compared across the two groups. Results There were a total of 29 patients, 12 with positive TMT and 17 with negative TMT. An abnormal magnetic field angle was more common in the TMT positive group (72% vs. 6%). Abnormal contour maps in the form of nondipole patterns or abnormal orientation were seen in 81.8% (9/11) patients in TMT positive group and 6.8% (1/17) patients in the TMT negative group ( p  < .001). Conclusion Abnormal magnetic field angle and abnormal magnetic field maps in MCG recorded at rest are able to identify the presence of coronary ischemia in patients with chronic chest pain and a normal resting ECG.

【 授权许可】

Unknown