Piezoresistive bridge microcantilevers biosensor based on SOI wafer for glucose detecting

Micro & nano letters

article

Feng Wen¹  Yuejin Zhao¹  Xiaomei Yu³ 

[1] School of Optoelectronics, Beijing Institute of Technology;National Key Laboratory for Electronic Measurement Technology, North University of China;National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Peking University

关键词: bioMEMS;    biosensors;    cantilevers;    chemical sensors;    microsensors;    monolayers;    piezoresistive devices;    resistors;    self-assembly;    sugar;    glucose solution concentration;    microcantilever bending;    4-mercaptophenylboronic acid;    self-assembled monolayer;    microcantilever gold-coated surface;    bulk silicon processes;    high-sensitivity piezoresistive four-set Wheatstone bridge structure microcantilever glucose biosensor;    glucose detection;    SOI wafer;    bioMEMS;    biosensors;    cantilevers;    chemical sensors;    microsensors;    monolayers;    piezoresistive devices;    resistors;    self-assembly;    sugar;    glucose solution concentration;    microcantilever bending;    4-mercaptophenylboronic acid;    self-assembled monolayer;    microcantilever gold-coated surface;    bulk silicon processes;    high-sensitivity piezoresistive four-set Wheatstone bridge structure microcantilever glucose biosensor;    glucose detection;    SOI wafer;   

DOI  :  10.1049/mnl.2013.0094

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Background: Airway maintenance procedures during anesthesia are usually associated with a rise in intraocular pressure (IOP). This is an important issue especially in vulnerable patients. In the present study we compared the rise in IOP with two different group of airway devices i.e. Laryngeal mask airway Supreme (LMA-S) and endotracheal intubation (ETT) using C-MAC® videolaryngoscope (VLS). Methodology: The present study was conducted on 100 adult patients of ages >18 yrs, of either sex, belonging to American Society of Anesthesiologist (ASA) I and II, scheduled to undergo non-ophthalmic elective surgery under general anesthesia. Patients were divided into two equal groups of 50 each, Group A and Group B. In group A (n = 50), lubricated appropriate sized LMA-S was inserted and in Group B (n=50), lubricated appropriate sized ETT was inserted by an anesthesiologist using VLS. IOP was measured in right eye just before insertion of device and subsequently at 1 min, 3 min, 5 min and 10 min after insertion of device. Hemodynamic parameters were recorded along with IOP measurement. Results: Both the groups were comparable regarding demographic data (p > 0.05), ASA grade (p = 0.069), and Mallampati grade (MPG) (p = 0.646). Airway establishment time (p = 0.011) was significantly less with C-MAC VLS. IOP were comparable at all measurement times, e.g., 1 min (p = 0.216), 3 min (p = 0.093), 5 min (p = 0.859) and 10 min (p = 0.060) after insertion of each device. Hemodynamic parameters measured were also comparable between two groups (p > 0.05). Conclusion: Both LMA Supreme and intubation using C-MAC® videolaryngoscope are safe regarding rise in intraocular pressure. Both methods can be safely used for airway management in suitable patients.

【 授权许可】

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