Magnetic biosensing system based on TSMC 0.35 um BioMEMS process for sensing magnetic nanobeads

Micro & nano letters

article

Wen Yaw Chung¹  Yi Ying Ye¹  Kimberly Jane Uy¹  Hao Chun Yang¹ 

[1] Department of Electronic Engineering, Chung Yuan Christian University

关键词: bioMEMS;    biosensors;    magnetic materials;    magnetic sensors;    proteins;    system-on-chip;    magnetic biosensing system;    BioMEMS;    magnetic nanobeads;    system-on-chip;    SoC;    protein;    antibodies;    TSMC 0.35;    biomicroelectromechanical systems;    front-end sensing;    signal processing;    biological fluids;    bioMEMS;    biosensors;    magnetic materials;    magnetic sensors;    proteins;    system-on-chip;    magnetic biosensing system;    BioMEMS;    magnetic nanobeads;    system-on-chip;    SoC;    protein;    antibodies;    TSMC 0.35;    biomicroelectromechanical systems;    front-end sensing;    signal processing;    biological fluids;   

DOI  :  10.1049/mnl.2013.0037

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Background & objectives: Several positions are used for performing subarachnoid block with varying difficulty of spinal access. Pendant position is known to reduce lumbar lordosis in patients’ especially pregnant patients making spinal access easier. The most ideal position for the easy spinal access is yet to be determined. This study was planned to compare ease of spinal access in pendant position vs. traditional sitting position (TSP) in pregnant females, and to establish the superiority of the former. Methodology: This randomized controlled trial was conducted in our hospital on 232 subjects over 6 month period. Parturients undergoing elective lower segment cesarean section (LSCS) were randomly divided into two groups: Group A (pendant group) and Group B (TSP group). Spinal puncture was performed at L3-L4 interspace, randomly making one of the two positions. Time for successful spinal, number of needle-to-bone contacts and total number of attempts were recorded. Results: The median age of the patients was 29 yrs with the interquartile range (IQR) 7. The number of needle-to-bone contacts in Group A was significantly higher compared to Group B (59.48% vs. 33.62%, p = 0.000). Mean time for successful spinal puncture was less in Group A than Group B (17.69 sec vs. 25.54 sec, p = 0.001). The difference in number of attempts for spinal in both positions was not significant. Conclusion: Pendant position is better than traditional sitting position in achieving successful spinal puncture in terms of needle-to-bone contacts and the time to puncture. However there is no difference in number of attempts for both positions.

【 授权许可】

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