Manipulation of DNA origami nanotubes in liquid using programmable tapping-mode atomic force microscopy

Micro & nano letters

article

Longhai Li¹  Xiaojun Tian¹  Zaili Dong¹  Lianqing Liu¹  Osamu Tabata³  Wen J. Li¹ 

[1] State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences;University of Chinese Academy of Sciences;Department of Micro Engineering, Kyoto University;Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg;Deparment of Mechanical and Biomedical Engineering, City University of Hong Kong

关键词: atomic force microscopy;    DNA;    micromechanical devices;    molecular biophysics;    nanobiotechnology;    nanotubes;    vibrations;    nanoelectromechanical devices;    nanoscale manipulation;    1D soft flexible DNA origami nanotubes;    DON;    mica substrate;    buffer solution;    programmable tapping-mode manipulation;    atomic force microscopy;    AFM tip tapping amplitude;    solution concentration;    single-point one-step manipulation;    AFM tip vibration amplitude;    optimised condition;    multipoint manipulation;    multistep manipulation;    nanomanipulation;    size 6 nm;    size 400 nm;   

DOI  :  10.1049/mnl.2013.0483

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Background & Objective: Hyperbaric bupivacaine 0.5% with fentanyl is often used for spinal anesthesia in lower segment cesarean section (LSCS). Its cardiotoxicity, extended sensory block and high sympathetic blocks in parturients can be disadvantageous. Levobupivacaine, an s-enantiomer of racemic bupivacaine is truly isobaric with CSF. It should be able to produce adequate sensory block with less hemodynamic changes and less cardiovascular toxicity. We aimed to evaluate the clinical efficacy of intrathecal 0.5% isobaric levobupivacaine compared to 0.5% hyperbaric bupivacaine with fentanyl 25 µg for elective LSCS.

【 授权许可】

CC BY|CC BY-ND|CC BY-NC|CC BY-NC-ND