Fabrication of silicon hierarchical nanopillar arrays based on nanosphere lithography

Micro & nano letters

article

Zongming Su¹  Xiao-Sheng Zhang¹  Wei Hu¹  Wen Liu¹  Mengdi Han¹  Haixia Zhang¹ 

[1] National Key Laboratory of Nano/Micro Fabrication Technology, Institute of Microelectronics, Peking University

关键词: silicon;    elemental semiconductors;    nanostructured materials;    nanofabrication;    nanolithography;    self-assembly;    semiconductor growth;    monolayers;    colloids;    masks;    sputter etching;    passivation;    silicon hierarchical nanopillar arrays;    nanosphere lithography;    self-assembled colloid particle monolayer;    evaporation-induced method;    masks;    deep reactive ion etching;    etching cycle optimisation;    passivation cycle optimisation;    double-layer hierarchical nanopillar arrays;    collapsing phenomenon;    Si;   

DOI  :  10.1049/mnl.2014.0260

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Background: The rapid onset and short duration of propofol makes it an idealanesthetic during esophagogastroduodenoscopy (EGD). Fentanyl is frequently used incombination with propofol during EGD to provide an analgesic component. The synergythat results from combining the two drugs may be beneficial but may also increasethe potential for apnea, hypotension, nausea, and prolonged recovery. This pilot studywas designed to test the hypothesis that propofol/fentanyl anesthesia provides betterconditions than propofol alone during EGD and to compare the incidence of sideeffects between the two techniques.Methodology: This was an IRB approved, double blinded, prospective, placebocontrolled study. One hundred consented patients undergoing EGD were randomlyassigned into two Groups. Patients in the first (propofol/fentanyl) Group receivedfentanyl 1 μg/kg followed by propofol 0.75 mg/kg bolus, while patients in the second(propofol) Group received propofol 1.5 mg/kg bolus. Patients in the Group that receivedfentanyl received half the initial induction dose of propofol in order to minimize thepotential for apnea and hypoventilation due to the synergy between the two drugs.In both Groups, additional 20 mg propofol boluses were given at 1min intervals untiladequate depth of anesthesia was reached. Propofol infusion was then started andadjusted to maintain adequate depth of anesthesia during the procedure. The primaryend point was the quality of anesthesia as rated by the blinded endoscopist. Thesecondary end points were the incidence of hypotension, hypoxia, nausea, vomiting,and delayed recovery. Data from the two Groups were compared by the Wilcoxon ranktest for the primary endpoint, by t-test for continuous measures, and by chi square forproportions including hypoxia and hypotension.

【 授权许可】

CC BY|CC BY-ND|CC BY-NC|CC BY-NC-ND