Poly( N -isopropylacrylamide)/polyurethane core–sheath nanofibres by coaxial electrospinning for drug controlled release

Micro & nano letters

article

Xiuling Lin¹  Dongyan Tang¹  Haitao Lyu³  Qingnan Zhang³ 

[1] State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology;Department of Materials Science and Engineering, Anhui University of Science and Technology;Department of Chemistry, Harbin Institute of Technology

关键词: nanofibres;    polymer fibres;    polymer blends;    nanofabrication;    nanomedicine;    electrospinning;    drug delivery systems;    drugs;    wetting;    nanocomposites;    fibre reinforced plastics;    poly(N-isopropylacrylamide)-polyurethane core-sheath nanofibres;    coaxial electrospinning;    drug controlled release;    drug carrier;    thermosensitivity;    soluble nifedipine;    nanofibre carriers;    diameter distribution;    outer flow rate;    inner flow rate;    wettability;    PNIPAAm-PU composite electrospun nanofibres;    toxicity;   

DOI  :  10.1049/mnl.2015.0503

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Patients with mitral stenosis associated with Pregnancy Induced Hypertension (PIH) continue to posea challenge to anesthesiologist and could be associated with an unfavorable maternal as well as fetaloutcome. Women with mitral stenosis often do not tolerate the cardiovascular demands of pregnancy.This increased volume load and tachycardia together cause the patients to deteriorate and advance fromone New York Heart association (NYHA) class to another. We report a, 28 year female, who underwentcesarean section under combined spinal-epidural anesthesia (CSEA). The uneventful course of theanesthesia in the presented case was due to the thorough systemic evaluation and careful anestheticstrategy.

【 授权许可】

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