Simple strategy for fabricating a Prussian blue/chitosan/carbon nanotube composite and its application for the sensitive determination of hydrogen peroxide

Micro & nano letters

article

Cong Wang¹  Keying Zhang¹  Na Zhang¹  Li Zhang¹  Hongyan Wang¹  Jigui Xu¹  Hongwei Shi¹  Xin Zhuo¹  Miao Qin¹  Xingxing Wu¹ 

[1] Key Laboratory of Spin Electron and Nanomaterials, School of Chemistry and Chemical Engineering, Suzhou University;College of Chemistry and Materials Science, Anhui Normal University

关键词: multi-wall carbon nanotubes;    hydrogen compounds;    electrochemical electrodes;    amperometric sensors;    nanofabrication;    reduction (chemical);    nanoparticles;    scanning electron microscopy;    Fourier transform infrared spectra;    iron compounds;    organic compounds;    catalysis;    electrochemistry;    nanosensors;    nanocomposites;    Prussian blue-chitosan-multiwalled carbon nanotube composite;    hydrogen peroxide sensitive determination;    chemical reaction;    Prussian blue nanoparticles;    electrode;    scanning electron microscopy;    Fourier transform infrared spectroscopy;    electrochemical hydrogen peroxide sensor;    electrocatalytic ability;    hydrogen peroxide reduction;    amperometric response;    C-Fe7(CN)18;    H2O2;   

DOI  :  10.1049/mnl.2016.0376

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

A 63-year-old man underwent right colon resection for cecal cancer following chemotherapy, followed by radiation therapy to the lung, liver and ischial bone metastases. He gradually developed right lower limb pain with numbness and his walking was affected markedly. He was admitted to the palliative care unit at our hospital for symptom management. Initially, we reasoned that the pain with numbness was caused by the cancerous invasion within the vertebral canal at S1, but oral oxycodone administration did not provide symptom relief. With the patient’s consent, we administered 4 mg of betamethasone in the subarachnoid space.1,2 after which the patient could walk with a walker. However, the walking instability with lower limb pain and numbness returned 2 weeks later. A second dose of subarachnoid betamethasone 4 mg was not fully effective. Due to development of a slight cognitive disorder, we performed brain magnetic resonance imaging, which revealed a 4×5 cm metastasis in his left frontal lobe. Ten doses of 3 Gy radiation and 40g daily of intravenous glycerin administration relieved his pain and resolved the motor disability. After this treatment, he could walk without walker and was discharged from our hospital. With daily intravenous glycerin administration and oral betamethasone, he could go traveling or to fitness center for about 1 month after discharge. Then he developed respiratory difficulty which was associated with extensive invasion of lung metastases, and intermittent or continuous sedation was added with his consent. He did not suffer the lower limb pain with numbness to when he died after 5 weeks after discharge. In the present case, the two cancer metastases, in the vertebral canal and brain were thought to have caused the lower limb pain with numbness. A comprehensive pain evaluation is important for cases involving complex cancer pain with numbness.

【 授权许可】

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