Conformation and electronic structure of DNA in carbon nanotubes: a molecular dynamics and first-principles study

Micro & nano letters

article

Zha Goujun¹  Zhang Fayun¹ 

[1]Xinyu University

关键词: DNA;    molecular biophysics;    molecular configurations;    electronic structure;    carbon nanotubes;    molecular dynamics method;    ab initio calculations;    nanobiotechnology;    DNA conformation;    electronic structure;    carbon nanotubes;    molecular dynamics method;    first principles study;    single-walled carbon nanotubes;    SWCNT;    π orbital;    conformational change;    ssDNA;    general-sequence oligonucleotide adsorption;    π-π stacking interactions;    electrostatic interactions;    torsional interactions;    sugar-phosphate backbone;    C;   

DOI  :  10.1049/mnl.2017.0030

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Aim: Limited availability and supply necessitates the rational use of blood and blood products and avoidance of unnecessary transfusion. A study was carried out in our tertiary care hospital over a period of two years to determine the usage of blood during different surgical procedures. Therefore, the ratio of units cross-matched to units transfused and transfusion probability were calculated. In this study, besides identifying the cases in which blood wastage was present, different factors and circumstances which affect Maximum Surgical Blood Order Schedule (MSBOS) were also noted. Methodology: After ethical committee approval and informed consent, 305 patients, ASA I and II, were inducted who were scheduled for elective surgical procedures. Parameters recorded were age, sex, hemoglobin, hematocrit, number of blood units crossmatched, duration of surgery, blood loss, type of anesthesia, cross-match to transfusion ratio (C/T), transfusion probability and transfusion index. Results: Among 305 patients, in the Obstetrics and Gynecology group the C/T ratio was 2.4 in cesarean section, in Surgery group it was maximum in open cholecystectomy (11), in the Urology group it was 6 in carcinoma bladder, in the spine surgeries it was 2.6 and in PDA ligation it was 7. Conclusion: By a team approach involving the surgeon, anesthesiologist and hematologist we can reduce the number and pattern of ordering blood for various surgeries.

【 授权许可】

CC BY|CC BY-ND|CC BY-NC|CC BY-NC-ND