Microfluidic device for super-fast evaluation of membrane protein nanoparticle formation

Micro & nano letters

article

H.-J. Wu¹  T. Basta¹  M. Morphew¹  D.C. Rees²  M.H.B. Stowell¹  Y.C. Lee¹ 

[1] Department of Mechanical Engineering;California Institute of Technology, Division of Chemistry and Chemical Engineering

关键词: biochemistry;    biodiffusion;    biomedical equipment;    biomembrane transport;    bioMEMS;    crystallisation;    lab-on-a-chip;    lipid bilayers;    microorganisms;    molecular biophysics;    molecular configurations;    nanofabrication;    nanoparticles;    proteins;    nanomedicine;    microfluidic device;    bi-layer lipids;    cell membrane;    inter-cell communication;    ionic-molecular transport;    biological bilayer lipid environment;    reconstitution-crystallisation process;    virus-like nanoparticles;    drug design;    drug delivery;    protein materials;    microelectromechanical system;    lab-on-a-chip;    membrane protein lipid nanoparticle formation;    convection-diffusion phenomena;    microfluidic channel;    syringe pump;    pharmacology;   

DOI  :  10.1049/mnl.2013.0216

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

I am writing in order to stress upon the correct and safe rate of propofol infusion in intensive care unit (ICU) as a high rate of infusion can easily be missed and can lead to serious consequences. Propofol infusion syndrome (PRIS) is a well-known entity, which has been reported in both children and adults and is related to its high rates. First death due to PRIS was reported in 1990. The term was originally coined in 1998 by Bray to describe the adverse effects with its use in pediatric population. Though the first case was reported in a child, it has now been increasingly reported in adult ICU patients too.

【 授权许可】

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