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Micro & nano letters
Free vibration analysis of a single-walled carbon nanotube embedded in an elastic matrix under rotational restraints
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Mustafa Özgür Yayli1 
[1] Department of Civil Engineering, Faculty of Engineering, Uludag University, 16059 Görükle Campus
关键词: single-wall carbon nanotubes;    elasticity;    vibrations;    Fourier series;    eigenvalues and eigenfunctions;    C;    matrix eigenvalues;    coefficient matrix;    Stokes transformation;    Fourier series;    mode shapes;    free vibration frequencies;    Eringen nonlocal elasticity;    rotationally restrained boundary conditions;    rotational restraints;    elastic matrix;    single-walled carbon nanotube;    free vibration analysis;   
DOI  :  10.1049/mnl.2017.0463
学科分类:计算机科学(综合)
来源: Wiley
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【 摘 要 】

Background: Irvingia gabonensis (Aubry-Lecomte ex O’Rorke) Baill. has been widely prescribed in African traditional medicine system for the management of hernia, yellow fever, gastrointestinal, liver conditions and sterility, as well as for some other ethno-medicinal uses. Aim: The study was to investigate the safety margins of ethanol extract of I. gabonensis root barks (EEIGRB) in Wistar rats. Setting: This research is a toxicology investigation. Methods: The acute and sub-acute toxicity studies conducted on the EEIGRB, according to the Organization for Economic Cooperation and Development (OECD) methods. Results: The acute toxicity studies revealed that LD 50 was > 5000 mg/kg. In the sub-acute study, significant increase in body weights ( p 0.05) changes in the haematological, hepatic and renal indices except for significant reduction ( p < 0.05) in serum concentrations of sodium and creatinine at 400 mg/kg of EEIGRB compared with control group. Histopathological examination of the liver and kidney revealed that at 200 mg/kg, there was a slight hepatic necrosis in the liver and a slight tubular necrosis in the kidney, whereas at 400 mg/kg, there was a moderate foci necrosis in the liver and a slight glomerular distortion occurred in the kidney. Conclusion: The results indicate that EEIGRB was found to be practically safe after acute administration, and there were histomorphological alterations in the liver and kidney after prolonged administration in the sub-acute dosages.

【 授权许可】

CC BY|CC BY-ND|CC BY-NC|CC BY-NC-ND   

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