Low-temperature synthesis of high-purity Ti 2 AlC powder by microwave sintering

Micro & nano letters

article

Weibing Zhou¹  Kang Li¹  Jiaoqun Zhu¹  Shouqin Tian³  Da-Ming Zhu² 

[1] School of Materials Science and Engineering, Wuhan University of Technology;University of Missouri-Kansas City;State Key Laboratory of Silicate Materials for Architecture, Wuhan University of Technology

关键词: titanium compounds;    aluminium compounds;    ionic conductivity;    vacancies (crystal);    sintering;    grain size;    ceramics;    high-purity powder;    facile microwave sintering;    charged vacancies;    ionic conductivity;    grain surface migration;    particle surface;    activation energy;    temperature 1300 degC to 850 degC;    Ti2AlC;   

DOI  :  10.1049/mnl.2018.0113

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Changes in the fluidity of membrane lipids are known to occur during aging and by lipid peroxidation. It is well documented that the fluidity state of the lipid phase in a membrane is important for the activity of intrinsic membrane proteins. Oxidants and fluidity of membrane lipids play a significant role in aging and age related neurodegenerative diseases. The aim of the present study was to determine the effect of tachykinin neuropeptide, Neurokinin B (NKB) and Amyloid beta fragment Aβ (25-35) on 17β estradiol (E2) treated aging female rat synaptosomes of different age groups. Aging brain functions were measured by membrane fluidity and fluorescent intensity with neuropeptides. An in-vitro incubation of Aβ (25-35) in E2 treated brain synaptosomes showed toxic effects on all the parameters. These effects of aging and Aβ (25–35) on membrane fluidity were restored by NKB and combined NKB and Aβ (25–35) with E2. Furthermore, we measured the Tryptophan (Trp) fluorescence to monitor changes in proteins and to make inferences regarding structure and dynamics. Trp is a sensitive marker of protein oxidation and its fluorescence significantly increased in E2 treated synaptosomes of aging rats. Furthermore, to evaluate the effect of oxidative stress on the membrane and protein conformation, fluorescent probe 1-Anilino-8-Naphthalenesulfonate ( ANS) were used. An increase in ANS fluorescence in E2 treated synaptosomes of aging rats indicated that E2 is associated with significant conformational changes and surface hydrophobicity of membranes and proteins.

【 授权许可】

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