Design and analysis of hairpin piezoresistive pressure sensor with improved linearity using square and circular diaphragms

Micro & nano letters

article

Mohsen Hayati¹  Morteza Fathipour²  Hamid Sherafat Vaziri¹ 

[1] Electrical Engineering Department, Faculty of Engineering, Razi University;Department of Electrical and Computer Engineering, University of Tehran

关键词: pressure sensors;    diaphragms;    resistors;    piezoelectric devices;    pressure measurement;    operational amplifiers;    circular diaphragm;    square diaphragm;    hairpin piezoresistive pressure sensor;    flat diaphragm;    piezoresistors;    OP-AMP amplifier;    COMSOL multiphysics software;   

DOI  :  10.1049/mnl.2018.0149

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

This study designed to prepare ultrafine apixaban (APX) o/w nanoemulsion (NE) based gel with droplet size below 50 nm as a good method for transdermal APX delivery without using permeation enhancer, alternatively, the formulation components itself act as permeation enhancer. APX, a potent oral anticoagulant drug that selectively and directly inhibit coagulation factor Xa, was selected as a good candidate for transdermal delivery as it displays poor water solubility (0.028 mg/mL) and low bioavailability (50%). APX-NE gel was prepared using triacetin, triton-x-100 and carbitol as oil phase, surfactant and cosurfactant respectively, while Carbopol 940 used as a gelling agent. Ex vivo permeation of APX-NE gel through human stratum corneum reveal.

【 授权许可】

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