Controllable synthesis of cuprite (Cu 2 O) microcrystals and their shape-dependent photocatalytic performances

Micro & nano letters

article

Peili Liu¹  Xu Zhang¹  Li Yao¹  Chengliang Han¹ 

[1] Department of Chemical and Material Engineering, Hefei University

关键词: copper compounds;    semiconductor materials;    crystal growth from solution;    semiconductor growth;    photochemistry;    catalysis;    crystal morphology;    X-ray diffraction;    scanning electron microscopy;    ultraviolet spectra;    visible spectra;    cuprite microcrystals;    shape-dependent photocatalytic performances;    octahedral morphology;    spherical morphology;    chemical method;    X-ray powder diffraction;    scanning electron microscopy;    potassium sodium tartrate;    gelatin addition;    UV-vis spectrophotometry;    direct bandgap semiconductor;    Cu2O;   

DOI  :  10.1049/mnl.2017.0495

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

CD-nanosponges were prepared by crosslinking B-CD with diphenylcarbonate (DPC) using ultrasound assisted technique. 5-FU was incorporated with NS by freeze drying, and the phase solubility study, complexation efficiency (CE) entrapment efficiency were performed. Also, the particle morphology was studied using SEM and AFM. The in-vitro release of 5-FU from the prepared nanosponges was carried out in 0.1N HCl. 5-FU nanosponges particle size was in the nano size. The optimum formula showed a particle size of (405.46±30) nm, with a polydispersity index (PDI) (0.328±0.002) and a negative zeta potential (-18.75±1.8). Also the drug entrapment efficiency varied with the CD: DPC molar ratio from 15.6 % to 30%. The SEM and AFM showed crystalline and porous nature of the nanosponges. The in vitro drug release study of the selected formula 5-FUNS2 exhibited the fastest dissolution rate which is 56% in the first hr. Different molar ratios of (cyclodextrin to crosslinker) (CD: DPC) has a proficient effect on complexation efficiency (CE), apparent stability constant (Kst) and entrapment efficiency of 5-FU. 5-FUNS2 with (1:4) molar ratio showed the best result of CE, Kst and entrapment efficiency. 5-FUNS2 gave a higher release rate than the 5-FU-BCD inclusion complex and 5-FU solution. Surface morphology of the prepared nanosponges by SEM, AFM indicate that nanosized and highly porous nanosponges was obtained. The overall results suggest that cyclodextrin nanosponges could be a promising 5-FU delivery system utilizing the suitable formula.

【 授权许可】

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