Micro & nano letters | |
Fog collection on a conical copper wire: effect of fog flow velocity and surface morphology | |
article | |
Haiting Xing1  Jiang Cheng1  Cailong Zhou1  Yanfen Zheng1  Gang Wang1  Xiufang Wen1  Pihui Pi1  Shouping Xu1  | |
[1] School of Chemistry and Chemical Engineering, South China University of Technology | |
关键词: contact angle; oxidation; fog; nanofabrication; wetting; copper; surface morphology; hydrophobicity; drops; wires; fog collection; conical copper wire; fog flow velocity; surface morphology; alkali assistant oxidation; leaf-like morphology; superhydrophobic CCWs; needle-like morphology; fog capture ability; | |
DOI : 10.1049/mnl.2017.0865 | |
学科分类:计算机科学(综合) | |
来源: Wiley | |
【 摘 要 】
Abstract The purpose of our study was to develop Dabigatran Etexilate loaded nanostructured lipid carriers (DE-NLCs) using Glyceryl monostearate and Oleic acid as lipid matrix, and to estimate the potential of the developed delivery system to improve oral absorption of low bioavailability drug, different Oleic acid ratios effect on particle size, zeta potential, entrapment efficiency and loading capacity were studied, the optimized DE-NLCs shows a particle size within the nanorange, the zeta potential (ZP) was 33.81±0.73mV with drug entrapment efficiency (EE%) of 92.42±2.31% and a loading capacity (DL%) of 7.69±0.17%. about 92% of drug was released in 24hr in a controlled manner, the ex-vivo intestinal permeation study using the non-everted sac model shows four folds increment in the permeation of DE-NLCs compared to dabigatran etexilate suspension (DE-S).
【 授权许可】
CC BY|CC BY-ND|CC BY-NC|CC BY-NC-ND
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202107100003044ZK.pdf | 338KB | download |