Approach for the improvement of sensitivity and sensing speed of TFET-based biosensor by using plasma formation concept

Micro & nano letters

article

Deepak Soni¹  Dheeraj Sharma¹  Mohd. Aslam¹  Shivendra Yadav¹ 

[1] Nanoelectronics and VLSI Lab, Electronics and Communication Engineering Discipline, Indian Institute of Information Technology

关键词: field effect transistors;    silicon;    elemental semiconductors;    biosensors;    tunnel transistors;    semiconductor device models;    sensing speed;    dual-gate source electrode dielectric-modulated tunnel field-effect transistor biosensor;    TFET;    biosensor;    Si-HfO2;   

DOI  :  10.1049/mnl.2018.5252

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

This study concerned with phytochemical investigation and methods of extraction and separation of active constituents from Valeriana officinalis plant cultivated in Iraq. Due to the large number of active constituents in Valeriana officinalis, it was necessary to make analytical study of its constituents to determine the chemical nature of these constituents and then determine the main classes (terpenes and iridoids) using chemical reagents specific for each class. Different organic solvents like ethanol (70%) used in soxhlet apparatus and hexane, ethyl acetate and methanol were used separately to extract the main active constituents by maceration. Through comparison between these solvents using thin layer chromatography (TLC), it has been found that hexane was best suited to extract most of the active constituents from the plant by maceration method. Analytical study showed that terpens was separated and purified using preparative TLC and preparative HPLC. Identification of isolated component (valtrate) from roots of plant was obtained using HPLC and PHPLC also depending on some material-specific constants such as infrared spectroscopy (FTIR). Results of analysis showed that Valeriana officinalis cultivated in Iraq is a good source of many constituents with different important pharmacological activities. The pharmacological study showed that the total organic plant extract has sleep induction effect when injected I.P. to experimental mice.  Key wards:  Valeriana officinalis, Valepotriate, Insomnia.

【 授权许可】

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