Synthesis, characterisation, and antimicrobial activity of ZnO-based nanocomposites

Micro & nano letters

article

Naser Faraji¹  Zahra Hajimahdi² 

[1] Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University;Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences

关键词: II-VI semiconductors;    manganese compounds;    antibacterial activity;    scanning electron microscopy;    nanoparticles;    X-ray diffraction;    nanocomposites;    copper compounds;    zinc compounds;    wide band gap semiconductors;    nanofabrication;    X-ray chemical analysis;    surface morphology;    Fourier transform infrared spectra;    crystal structure;    X-ray diffraction;    XRD;    high-antimicrobial activity;    nanocomposites;    FTIR;    scanning electron microscopy;    energy dispersive X-ray spectroscopy;    gram-positive Staphylococcus aureus;    gram-negative Escherichia coli;    crystalline structure;    surface morphology;    Fourier transform infrared spectra;    colony forming count method;    ZnO-MnO-CuO;   

DOI  :  10.1049/mnl.2018.5202

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Present study was carried out to find prevalence of MRSA in healthy individual of second stage students, college of pharmacy/Baghdad University. A total of 74 student selected between age 18-23 years old were included in this study, nasal swabs collected and subjected to many diagnostic standard bacteriological identification methods. Culture, colonial morphology, Gram stain,  mannitol fermentation, coagulase ,gelatinasetest, DNAase, MR/VP and antimicrobial susceptibility test was performed on tryptic soy agar by modified Kirby-Bauer muller hinton disc diffusion method and the result show that out of 74 nasal swabs,67(90.5%) were MRSA positive isolates, 21(31.4%) of them were mannitol ferment and 46(68.6%) non mannitol fermenter, among these isolates 33(44.6%)male and 41(55.4%) female, there was no significant sex difference in the prevalence of Staph. aureus, while show decrease in prevalence with age group,(54%),(27%),(9.5%) alternatively, MRSA positive isolates indicated relatively high rate of resistance to antibiotics, so to vancomycin 3(4.5%),ciprofloxacin 4(6%) , tetracyclin 9(13.5%) ,gentamycin  6(9%),  erythromycin 15(22.5%) and keflex 20(30%). This study show a  high  prevalence  of  MRSA  carriage  in  young  adult  college  student (healthy people) that indicating  the spread of MRSA in the community which consider high risk of spreading infections also we isolate  non  mannitol  fermenter  (MRSA)  Staph. aureus that need further moleculer analysis to prove it.

【 授权许可】

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