Preparation, characterisation and enhanced photocatalytic activities of Fe,F co-doped TiO 2 nanotubes

Micro & nano letters

article

Zhuanni Yu¹  Jing Lan¹  Qiang Wang¹ 

[1] College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University

关键词: catalysts;    transmission electron microscopy;    catalysis;    ultraviolet spectra;    X-ray photoelectron spectra;    semiconductor materials;    semiconductor nanotubes;    iron;    nanofabrication;    nanoparticles;    titanium compounds;    visible spectra;    X-ray diffraction;    photochemistry;    scanning electron microscopy;    semiconductor growth;    enhanced photocatalytic activities;    Fe monodoped TiO2 nanotubes;    hydrothermal process;    impregnation method.;    XRD;    X-ray diffraction;    TiO2Fe;    F;    time 1.0 s;    visible light irradiation;    photodegrading aqueous methyl orange;    TiO2lattice;    F 1s;    Fe 2P;    TEM images;    high-resolution XPS spectra;    anatase phase;    X-ray photoelectron spectroscopy;    TEM;    transmission electron microscopy;   

DOI  :  10.1049/mnl.2018.5318

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

4-chloro and 4- nitro substituted phenol and aniline incorporated to a carboxylic group of naproxen a well-known non-steroidal anti-inflammatory drug (NSAID) to increase bulkiness were synthesized for evaluation as  a potential anti-inflammatory agents with expected COX-2 selectivity. In vivo acute anti-inflammatory activity of these compounds (I-IV) was evaluated in rats using egg-white induced edema model of inflammation in a dose equivalent to (2.5 mg/Kg) of naproxen. All tested compounds produced a significant reduction in paw edema with respect to the effect of propylene glycol 50% v/v (control group). Moreover, compounds I and IV might show higher effect comparable to that of naproxen and to that of compounds II & III which may attribute to the higher effect of nitro group than chloride group. The results of this study indicate that esterification and amidation of naproxen with selected pharmacophoric groups enhance or maintain its anti-inflammatory activity.      Keywords: anti-inflammatory; naproxen derivatives.

【 授权许可】

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