Development and characterisation of glucosamine sulphate magnetic nanoparticles for rheumatoid arthritis chemotherapy

Micro & nano letters

article

Latha Subbiah¹  Selvamani Palanisamy¹  Deepak B. Thimiri Govinda Raj² 

[1] Department of Pharmaceutical Technology, Centre for Excellence in Nanobio Translational Research, Anna University, Bharathidasan Institute of Technology Campus;Synthetic Biology Centre

关键词: patient treatment;    nanoparticles;    drugs;    magnetic particles;    diseases;    nanomedicine;    cellular biophysics;    biomedical materials;    cancer;    molecular biophysics;    biochemistry;    drug delivery systems;    glucosamine sulphate magnetic nanoparticles;    rheumatoid arthritis chemotherapy;    autoimmune disease;    synovial joints;    associated regions;    targetted drug delivery;    anti-rheumatic drugs;    magnetically targetted RA chemotherapy;   

DOI  :  10.1049/mnl.2019.0748

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Rheumatoid arthritis (RA) is an autoimmune disease that principally attacks synovial joints. RA also cause inflammation in the joints and associated regions. There is an unmet medical need for RA as well as for the targetted drug delivery of anti-rheumatic drugs to improve its efficacy at a much lower doses while decreasing its side effects. Hence, in this Letter, the authors report the development and characterisation of glucosamine sulphate magnetic nanoparticles for magnetically targetted RA chemotherapy.

【 授权许可】

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