IJU Case Reports | |
Successful recovery from coronavirus disease 2019 in a living kidney transplant recipient using low-dose methylprednisolone | |
article | |
Ryo Tanaka1  Yoichi Kakuta1  Koichi Tsutahara1  Masahiro Nakagawa1  Naotsugu Ichimaru2  Katsuhiko Sakaguchi2  Taigo Kato3  Ryoichi Imamura3  Norio Nonomura3  Tetsuya Takao1  | |
[1] Department of Urology;Kidney Center, Sumitomo Hospital;Department of Urology, Osaka University Graduate School of Medicine | |
关键词: COVID-19; immunosuppressive therapy; kidney transplantation; low-dose methylprednisolone; solid organ transplant; | |
DOI : 10.1002/iju5.12226 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Wiley | |
【 摘 要 】
Introduction The data of immunosuppressive therapy management on solid organ transplant recipients with coronavirus disease 2019 are insufficient. We report a kidney transplant recipient who developed coronavirus disease 2019 pneumonia, with successful management of low-dose mPSL. Case presentation A 36-year-old man, who underwent living kidney transplantation 1.5 year prior, developed fever. After 10 days, he developed dyspnea, and his blood oxygen levels decreased. Computed tomography showed pulmonary ground-glass shadow on both lungs, and the coronavirus disease 2019 real-time polymerase chain reaction test was positive. After reducing the immunosuppressive agents, the C-reactive protein levels continued elevating, and the pulmonary shadow spread. Subsequently, low-dose methylprednisolone (40 mg/day) was administered for 4 days and his C-reactive protein and blood oxygen levels increased and improved, respectively. The coronavirus disease 2019 real-time polymerase chain reaction test was negative and the pulmonary shadow disappeared. Conclusion Low-dose methylprednisolone may prevent the development of severe coronavirus disease 2019.
【 授权许可】
CC BY|CC BY-NC|CC BY-NC-ND
【 预 览 】
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RO202107100001314ZK.pdf | 440KB | download |