Cellular and molecular mechanisms of various types of oocyte aging

Reproductive medicine and biology

article

Toshifumi Takahashi¹  Hideki Igarashi¹  Mitsuyoshi Amita¹  Shuichiro Hara¹  Hirohisa Kurachi¹ 

[1] Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine

关键词: Calcium regulation Oocyte aging Ovarian aging Oxidative stress Postovulatory oocyte aging;   

DOI  :  10.1007/s12522-011-0099-0

学科分类：工业工程学

来源: Wiley

【 摘 要 】

Background:  A diarrheal disease is an endemic disease and has outbreak potential in Indonesia. In Indonesia (2012) the number of pain diarrhea on toddler reached 900 per 1,000 inhabitants. This study aimed to determine the factors associated to the incidence of diarrhea in infant aged 6-12 months.   Subjects and Method: This was an observational analytic study with cross sectional design. This was conducted in Karanganyar Community Health Center, Purbalingga, Indonesia, in April-Mei 2016. A total of 100 subjects was selected Fixed Disease. The data was using the questionnaire. The data analysis used path analysis. Results: There was a direct correlation between breast feeding, nutritional status, personal hygiene of mothers and infants, and the availability of basic sanitation with the incidence of diarrhea, and statistically significant (b= 2.62; 95% CI= 1.00 to 4.24; p= 0.001), (b= 3.37; 95% CI = 0.61 to 6.12; p=0.017), (b=3.70; 95% CI=2.07 to 5.33; p<0.001), (b=3.00; 95% CI=0.69 to 5.32; p=0.011). There is a positive correlation between indirect breast feeding with the incidence of diarrhea through nutritional status, culture with the incidence of diarrhea through breast feeding, culture with the incidence of diarrhea through the facility's individual mothers and babies, the availability of basic sanitation with diarrhea through individual facility's mothers and babies, statistically significant (b=0.91;  95%CI =-0.28 to2.11;p=0.135), (b=1.83; 95% CI=0.95 to 2.22; p<0.001), (b=1.40; 95% CI=0.46 to 2.25; p=0.003), (b=1.10; 95% CI= -0.10 to 2.22; p=0.076). Conclusion: There is a direct correlation between breast feeding, nutritional status, personal hygiene of mothers and infants, and the availability of basic sanitation with the incidence of diarrhea. There is indirect correlation between breast milk with the incidence of diar­rhea through nutritional status, culture, personal of mother and infants, the availability of basic sani­tation with diarrhea through individual facility's mother and the baby.

【 授权许可】

CC BY|CC BY-NC|CC BY-NC-ND