Macular pucker, an atypical clinical presentation of ocular toxoplasmosis: a case report

BMC Ophthalmology

Chun-yan Xue¹  Zheng-gao Xie²  Si Zhang²  Ya-jun Liu²  Wen-wen Zhang² 

[1] Department of Ophthalmology, Jinling Hospital, Nanjing University School of Medicine, 210008, Nanjing, Jiangsu Province, China;Department of Ophthalmology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 210008, Nanjing, Jiangsu Province, China;

关键词: Epiretinal membrane;    Macular pucker;    Ocular toxoplasmosis;    Toxoplasma gondii;    Intraocular fluid testing;    Serologic testing;   

DOI  :  10.1186/s12886-021-01983-7

来源: Springer

【 摘 要 】

BackgroundOcular toxoplasmosis caused by Toxoplasma gondii is an infectious disease which is widely distributed around the world and can present with various clinic manifestations. We are here reporting an unusual case presented with epiretinal membrane (ERM), i.e., macular pucker.Case presentationA 16-year old male patient visited our outpatient clinic complaining of decreased vision for about 8 years in his left eye. The best-corrected visual acuity (BCVA) was 20/20 OD and 20/400 OS. There was sensory exotropia in his left eye. No inflammatory cells or flare were found in his anterior chamber or vitreous cavity OU. An ERM involving his left macular area was found on his dilated fundus exam, which was confirmed by Optical Coherence Tomography (OCT). The ERM was found to involve his left macular area with his foveal ellipsoid zone absent. The right eye was found to be within normal limit.After a thorough discussion with the patient and his parents about treatment options and surgical benefits, risks and alternatives, we performed vitrectomy, peeled off the ERM and collected the vitreous sample for parasite testing during the procedure. Patient’s blood also was drawn for serological testing. Vitreous sample analysis and serological tests confirmed ocular toxoplasmosis OS as his final diagnosis. Unfortunately, the BCVA of this patient was not improved after the surgery, but the exotropia disappeared.ConclusionERM is an unusual clinical presentation of ocular toxoplasmosis. We may add Toxoplasma gondii infection as a differential diagnosis when encountering ERM cases.

【 授权许可】

CC BY