Epidemiological trends of maternal hypertensive disorders of pregnancy at the global, regional, and national levels: a population‐based study

BMC Pregnancy and Childbirth

Xin Xie¹  Fei Zhao²  Ting Yuan²  Wei Wang²  Yanyan Wang²  Zhangjian Zhou³  Hao Zhang⁴ 

[1] Department of Nuclear Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, 710061, Xi’an, Shaanxi, China;Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xi’an Jiaotong University, 710061, Xi’an, Shaanxi, China;Department of Oncology, The Second Affiliated Hospital of Xi’an Jiaotong University, 710004, Xi’an, Shaanxi, China;Department of Surgical Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, 710061, Xi’an, Shaanxi, China;Department of Public Health, Baoji High-tech People’s Hospital, 721000, Baoji, Shaanxi, China;

关键词: Hypertensive disorders of pregnancy;    Burden of disease;    Sociodemographic index;    Human development index;   

DOI  :  10.1186/s12884-021-03809-2

来源: Springer

【 摘 要 】

BackgroundRelevant studies focusing on epidemiological of profiles hypertensive disorders of pregnancy from global data that report the cause-specific prevalence and trends of hypertensive disorders of pregnancy at global, regional and national levels from 1990 to 2019 by age and sociodemographic index are still limited.MethodsFor hypertensive disorders of pregnancy, point prevalence, annual incidence, and years lived with disability numbers and age standardized rates per 100,000 population were compared at regional and national levels by age and sociodemographic index using data from the global Burden of Disease 2019 Study, covering populations from 204 countries and territories. Estimates are reported with uncertainty intervals to exhibit the changing trends during a specific period.ResultsThe incidence of hypertensive disorders of pregnancy increased from 16.30 million to 18.08 million globally, with a total increase of 10.92 % from 1990 to 2019. The age-standardized incidence rate decreased, with an estimated annual percent change of -0.68 (95 % confidence interval [CI] -0.49 to -0.86). The number of deaths due to hypertensive disorders of pregnancy was approximately 27.83 thousand in 2019, representing a 30.05 % decrease from 1990. Based on the incidence and prevalence, the number of deaths and years lived with disability were highest in the group aged 25–29 years, followed by the groups aged 30–34 and 20–24 years, while the lowest estimated incidence rate was observed in the group aged 25–29 years and higher incidence rates were observed in the youngest and oldest groups. Positive associations between incidence rates and the sociodemographic index and human development index were found for all countries and regions in 2019. Age-standardized incidence rates were higher in countries/regions with lower sociodemographic indices and human development indices.ConclusionsOur study provides a comprehensive overview of the global burden of hypertensive disorders of pregnancy. The death and incidence rates are decreasing in most countries and all regions except for those with low sociodemographic and human development indexes. This difference is mainly due to the increasing attention to prenatal examinations and health education. Further investigations should focus on forecasting the global disease burden of specific hypertensive disorders of pregnancy and modifiable risk factors.

【 授权许可】

CC BY