Patient hematology during hospitalization for viral pneumonia caused by SARS-CoV-2 and non-SARS-CoV-2 agents: a retrospective study

European Journal of Medical Research

Shaojie Xin¹  Jun Hou²  Shengdong Luo²  Rong Gao²  Zengtao Yao²  Panyong Mao²  Yan Hu²  Yenv Ma²  Bingke Bai²  Hongyan Gao²  Mengmeng Qu²  Juan Cheng³  Zhe Xu³ 

[1] Liver Failure Treatment and Research Center, Fifth Medical Center of Chinese, PLA General Hospital, 100 Middle Street of 4th West Ring Road, 100039, Beijing, China;Research Center of Clinical and Translational Medicine, Fifth Medical Center of Chinese, PLA General Hospital, 100 Middle Street of 4th West Ring Road, 100039, Beijing, China;Treatment and Research Center for Infectious Diseases, Fifth Medical Center of Chinese, PLA General Hospital, 100 Middle Street of 4th West Ring Road, 100039, Beijing, China;

关键词: Hematology;    SARS-CoV-2;    COVID-19;    Adenovirus;    H1N1;   

DOI  :  10.1186/s40001-021-00515-9

来源: Springer

【 摘 要 】

BackgroundHematological comparison of coronavirus disease (COVID-19) and other viral pneumonias can provide insights into COVID-19 treatment.MethodsIn this retrospective case–control single-center study, we compared the data of 126 patients with viral pneumonia during different outbreaks [severe acute respiratory syndrome (SARS) in 2003, influenza A (H1N1) in 2009, human adenovirus type 7 in 2018, and COVID-19 in 2020].ResultsOne of the COVID-19 characteristics was a continuous decline in the hemoglobin level. The neutrophil count was related to the aggravation of COVID-19 and SARS. Thrombocytopenia occurred in patients with SARS and severe COVID-19 even at the recovery stage. Lymphocytes were related to the entire course of adenovirus infection, recovery of COVID-19, and disease development of SARS.ConclusionsDynamic changes in hematological counts could provide a reference for the pathogenesis and prognosis of pneumonia caused by respiratory viruses in clinics.

【 授权许可】

CC BY