COVID-19 vaccine testing & administration guidance for allergists/immunologists from the Canadian Society of Allergy and Clinical Immunology (CSACI)

Allergy, Asthma & Clinical Immunology

Lori Connors¹  Elissa M. Abrams²  Anne K. Ellis³  Edmond S. Chan⁴  Julia E. M. Upton⁵  Beata Derfalvi⁶  Timothy K. Vander Leek⁷ 

[1] Department of Medicine, Dalhousie University, Halifax, NS, Canada;Department of Pediatrics, Section of Allergy and Clinical Immunology, University of Manitoba, Winnipeg, MN, Canada;Department of Pediatrics, Division of Allergy and Immunology, University of British Columbia, Vancouver, BC, Canada;Division of Allergy & Immunology, Department of Medicine, Queen’s University, Kingston, ON, Canada;Division of Allergy and Immunology, Department of Pediatrics, University of British Columbia, BC Children’s Hospital, Vancouver, BC, Canada;Division of Immunology and Allergy, Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada;Division of Immunology, Department of Pediatrics, Dalhousie University/IWK Health Centre, Halifax, NS, Canada;Pediatric Allergy and Asthma, Department of Pediatrics, University of Alberta, 207-10430 61 Ave NW, T6H 2J3, Edmonton, AB, Canada;

关键词: COVID-19;    Vaccine;    PEG;    Allergy;    Anaphylaxis;    Immunocompromise;    Immune deficiency;   

DOI  :  10.1186/s13223-021-00529-2

来源: Springer

【 摘 要 】

BackgroundSafe and effective vaccines provide the first hope for mitigating the devastating health and economic impacts resulting from coronavirus disease 2019 (COVID-19) and related public health orders. Recent case reports of reactions to COVID-19 vaccines have raised questions about their safety for use in individuals with allergies and those who are immunocompromised. In this document, we aim to address these concerns and provide guidance for allergists/immunologists.MethodsScoping review of the literature regarding COVID-19 vaccination, adverse or allergic reactions, and immunocompromise from PubMed over the term of December 2020 to present date. We filtered our search with the terms “human” and “English” and limited the search to the relevant subject age range with the term “adult.” Reports resulting from these searches and relevant references cited in those reports were reviewed and cited on the basis of their relevance.ResultsAssessment by an allergist is warranted in any individual with a suspected allergy to a COVID-19 vaccine or any of its components. Assessment by an allergist is NOT required for individuals with a history of unrelated allergies, including to allergies to foods, drugs, insect venom or environmental allergens. COVID-19 vaccines should be offered to immunocompromised patients if the benefit is deemed to outweigh any potential risks of vaccination.InterpretationThis review provides the first Canadian guidance regarding assessment of an adolescent and adult with a suspected allergy to one of the COVID-19 vaccines currently available, or any of their known allergenic components, and for patients who are immunocompromised who require vaccination for COVID-19. As information is updated this guidance will be updated accordingly.

【 授权许可】

CC BY