Land use impacts on parasitic infection: a cross-sectional epidemiological study on the role of irrigated agriculture in schistosome infection in a dammed landscape

Infectious Diseases of Poverty

M. Moustapha Sam¹  Simon Senghor¹  Assane Fall¹  Anne-Marie Schacht²  Gilles Riveau²  David H. Rehkopf³  David Lopez-Carr⁴  Andrea J. Lund⁵  Giulio A. De Leo⁶  Nicolas Jouanard⁷  Susanne H. Sokolow⁸ 

[1] Centre de Recherche Biomédicale-Espoir Pour La Sante, BP 226, 263 Route de la Corniche, Saint-Louis, Sénégal;Centre de Recherche Biomédicale-Espoir Pour La Sante, BP 226, 263 Route de la Corniche, Saint-Louis, Sénégal;Center for Infection and Immunology of Lille, Institut Pasteur de Lille, 1 Rue du Professeur Calmette, 59800, Lille, France;Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford University, 1701 Page Mill Road Room 229, Palo Alto, CA, USA;Department of Geography, University of California, 4836 Ellison Hall, Santa Barbara, CA, USA;Emmett Interdisciplinary Program in Environment and Resources, Stanford University, 473 Via Ortega Suite 226, Stanford, CA, USA;Hopkins Marine Station, Stanford University, 120 Ocean View Blvd, Pacific Grove, CA, USA;Station d’Innovation Aquacole, UGB Cote Cite SAED, BP 524, Saint-Louis, Sénégal;Center for Infection and Immunology of Lille, Institut Pasteur de Lille, 1 Rue du Professeur Calmette, 59800, Lille, France;Woods Institute for the Environment, Stanford University, 473 Via Ortega, Stanford, CA, USA;Hopkins Marine Station, Stanford University, 120 Ocean View Blvd, Pacific Grove, CA, USA;

关键词: Agriculture;    Exposure;    Livelihoods;    Planetary health;    Senegal;    Schistosomiasis;    Water contact;   

DOI  :  10.1186/s40249-021-00816-5

来源: Springer

【 摘 要 】

BackgroundWater resources development promotes agricultural expansion and food security. But are these benefits offset by increased infectious disease risk? Dam construction on the Senegal River in 1986 was followed by agricultural expansion and increased transmission of human schistosomes. Yet the mechanisms linking these two processes at the individual and household levels remain unclear. We investigated the association between household land use and schistosome infection in children.MethodsWe analyzed cross-sectional household survey data (n = 655) collected in 16 rural villages in August 2016  across demographic, socio-economic and land use dimensions, which were matched to Schistosoma haematobium (n = 1232) and S. mansoni (n = 1222) infection data collected from school-aged children. Mixed effects regression determined the relationship between irrigated area and schistosome infection presence and intensity.ResultsControlling for socio-economic and demographic risk factors, irrigated area cultivated by a household was associated with an increase in the presence of S. haematobium infection (odds ratio [OR] = 1.14; 95% confidence interval [95% CI]: 1.03–1.28) but not S. mansoni infection (OR = 1.02; 95% CI: 0.93–1.11). Associations between infection intensity and irrigated area were positive but imprecise (S. haematobium: rate ratio [RR] = 1.05; 95% CI: 0.98–1.13, S. mansoni: RR = 1.09; 95% CI: 0.89–1.32).ConclusionsHousehold engagement in irrigated agriculture increases individual risk of S. haematobium but not S. mansoni infection. Increased contact with irrigated landscapes likely drives exposure, with greater impacts on households relying on agricultural livelihoods.

【 授权许可】

CC BY