Effects of running a marathon on irisin concentration in men aged over 50

The journal of physiological sciences

article

Paweł Jóźków¹  Dawid Koźlenia¹  Katarzyna Zawadzka²  Marek Konefał³  Paweł Chmura³  Katarzyna Młynarska⁴  Michał Kosowski⁴  Marek Mędraś¹  Jan Chmura³  Piotr Ponikowski⁴  Jacek Daroszewski² 

[1] Department of Sports Medicine and Dietetics, Wroclaw University of Physical Education;Department of Endocrinology, Wroclaw Medical University;Department of Team Sport Games, Wroclaw University of Physical Education;Department of Heart Diseases, Medical University

关键词: Irisin;    Endurance training;    Running;    Marathon;    Men;   

DOI  :  10.1007/s12576-018-0619-3

来源: Springer

【 摘 要 】

Our aim was to verify whether running a marathon is associated with changes in irisin concentration in healthy, endurance-trained men. In an observational study, we assessed baseline biochemical and fitness parameters of 28 middle-aged runners (mean ± SD age, BMI, VO2max: 58 ± 8 years; 24.5 ± 3 kg/m2; 51.1 ± 1.7 ml/kg/min). We evaluated irisin before, immediately after, and 7 days after the marathon. Irisin concentration decreased from a baseline value of 639 ± 427 to 461 ± 255 ng/ml immediately after the marathon (p < 0.05). After 7 days, it was still significantly lower than before the race, at 432 ± 146 ng/ml (p < 0.05). We found no correlations between irisin concentration and the training history of the studied subjects. We conclude that a long-distance run may have a negative impact on irisin release in men. This effect was not correlated with the training history of runners.

【 授权许可】

Unknown