A pilot randomized controlled trial of 6-week combined exercise program on fasting insulin and fitness levels in individuals with spinal cord injury

European spine journal

article

Dong-Il Kim¹  J. Andrew Taylor²  Can Ozan Tan²  Hyuna Park⁵  Ji Young Kim⁶  Sang-Yong Park⁷  Kyong-Mee Chung⁸  Young-Hee Lee⁹  Bum-Suk Lee^1,10  Justin Y. Jeon⁵ 

[1] Department of Professional Therapy, Graduate School of Professional Therapy, Gachon University;Department of Physical Medicine and Rehabilitation, Harvard Medical School;Cardiovascular Research Laboratory, Spaulding Hospital Cambridge;Cerebrovascular Research Laboratory, Spaulding Rehabilitation Hospital;Department of Sport Industry Studies, Exercise Medicine and Rehabilitation Laboratory, Yonsei University;Korea Disabled People’s Development Institute;Department of Physical Education, Gachon University;Department of Psychology, Yonsei University;Department of Rehabilitation Medicine, Yonsei University Wonju College of Medicine;Department of Rehabilitation Medicine, National Rehabilitation Hospital

关键词: Spinal cord injury;    Exercise;    Body composition;    Fitness;    Insulin;   

DOI  :  10.1007/s00586-019-05885-7

来源: Springer

【 摘 要 】

The aim of this randomized controlled trial study was to investigate the effect of combined exercise program on the fasting insulin and fitness levels of people with spinal cord injury (SCI). A total of 19 individuals with SCI participated in a combined exercise program consisting of aerobic and resistance exercises for 60 min per day, 3 days per week for 6 weeks. Peak oxygen consumption, body mass index, percent body fat, waist circumference, shoulder abduction and adduction, shoulder flexion and extension, elbow flexion and extension, fasting insulin levels, and homeostasis model assessment of insulin resistance (HOMA-IR) levels were measured at baseline and after the intervention. The 6-week exercise program significantly decreased the average fasting insulin (baseline: 7.5 ± 4.7 µU/ml vs. post-intervention: 4.5 ± 2.2 µU/ml, p < 0.05) and HOMA-IR (baseline: 1.5 ± 1.0 vs. post-intervention: 0.9 ± 0.4, p < 0.05) in the exercise group, whereas there was no change in control group (between group difference, mean fasting insulin: − 3.2 µU/ml, p = 0.003; mean HOMA-IR: − 0.66, p = 0.001). In addition, muscle strength of the shoulder flexors, extensors, abductors, adductors, and elbow flexors was significantly improved in the exercise group compared to the controls. A combined exercise program is effective in decreasing fasting insulin and HOMA-IR levels while improving fitness in those with SCI. These slides can be retrieved under Electronic Supplementary Material.

【 授权许可】

Unknown