Evaluation of general repolarization of cardiomyocites with biphasic pulses of different shapes

Cardiometry

article

Nikolay N. Chernov¹  Aleksandr A. Bezverkhii¹  Vladimir I. Timoshenko¹ 

[1] Southern Federal University

关键词: Biphasic pulse;    Defibrillation;    Cardiomyocytes repolarization;    Ventricular fibrillation;    Current-controlled defibrillation;   

DOI  :  10.12710/cardiometry.2020.16.8084

学科分类：环境科学（综合）

来源: Russian New University

【 摘 要 】

According to data provided by the European Resuscitation Council (ERC), 76% of sudden cardiac arrests should be attributed to ventricular fibrillation [1-3]. The main treatment of this disease is an immediate cardiopulmonary resuscitation, one of the components of which is a defibrillation of abnormal rhythms. The paper presents an analysis of advanced shapes of biphasic pulses, which have found a widespread application and have been clinically tested. The aim is to study the main parameters of the impact of different shapes of the existing pulses and their due consideration in a development of a defibrillator. An evaluation has been performed using defibrillators Fluke Impulse 7000DP and device Impulse 7010 designed to simulate different loads. Evaluated has been the shape of each of 7 biphasic pulses, the amplitude and exposure time of each of different signal phases. Upon results of the conducted analysis, some recommendations on cardiopulmonary resuscitation have been prepared; in particular, the necessity to maintain a constant current density of 14 -16 A, delivered for 4 -5 ms, is proposed. The maintenance of these parameters can be provided using the current stabilization technology (CST).

【 授权许可】

CC BY