Investigating the relevance of major signaling pathways in cancer survival using a biologically meaningful deep learning model

BMC Bioinformatics

Heming Zhang¹  Jiarui Feng²  Fuhai Li³ 

[1] Institute for Informatics (I2), Washington University School of Medicine, Washington University in St. Louis, St. Louis, MO, USA;Computer Science, Washington University School of Medicine, Washington University in St. Louis, St. Louis, MO, USA;Institute for Informatics (I2), Washington University School of Medicine, Washington University in St. Louis, St. Louis, MO, USA;Data Science, Washington University School of Medicine, Washington University in St. Louis, St. Louis, MO, USA;Institute for Informatics (I2), Washington University School of Medicine, Washington University in St. Louis, St. Louis, MO, USA;Department of Pediatrics, Washington University School of Medicine, Washington University in St. Louis, St. Louis, MO, USA;

关键词: Deep learning;    Survival analysis;    Signaling pathways;    TCGA;   

DOI  :  10.1186/s12859-020-03850-6

来源: Springer

【 授权许可】

CC BY