Myopalladin promotes muscle growth through modulation of the serum response factor pathway

Journal of Cachexia, Sarcopenia and Muscle

Marco Caremani¹  Marco Linari¹  Irene Pertici¹  Vinay K. Kadarla²  Moriah R. Beck²  Giuseppina Mastrototaro³  Simone Serio³  Daniel L. Yamamoto⁴  Marie‐Louise Bang⁵  Maria Carmela Filomena⁵  Ralph Knöll⁶  Anupama Vydyanath⁷  Pradeep K. Luther⁷  Richard L. Lieber⁸  Margherita Mutarelli⁹  Vincenzo Nigro^1,10  Arcamaria Garofalo^1,10 

[1] Department of Biology, University of Florence, Sesto Fiorentino, Florence, Italy;Department of Chemistry, Wichita State University, Wichita, KS, USA;Humanitas Clinical and Research Center, Rozzano, Milan, Italy;Institute of Genetic and Biomedical Research (IRGB), Milan Unit, National Research Council, Milan, Italy;Institute of Genetic and Biomedical Research (IRGB), Milan Unit, National Research Council, Milan, Italy;Humanitas Clinical and Research Center, Rozzano, Milan, Italy;Integrated Cardio Metabolic Centre (ICMC), Myocardial Genetics, Karolinska Institutet, University Hospital, Heart and Vascular Theme, Sweden;Research and Early Development, Cardiovascular, Renal and Metabolic Diseases (CVRM), Biopharmaceuticals R&D, AstraZeneca, Mölndal, Sweden;National Heart and Lung Institute, Imperial College London, London, UK;Shirley Ryan AbilityLab and Hines V.A. Medical Center Chicago, Chicago, IL, USA;Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA;Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA;Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy;Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy;Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy;

关键词: Skeletal muscle;    Sarcomere;    Knockout mouse;    Muscle growth;    Actin dynamics;    Serum response factor pathway;   

DOI  :  10.1002/jcsm.12486

来源: Wiley

【 授权许可】

CC BY