Prohibitin depletion extends lifespan of a TORC2/SGK‐1 mutant through autophagy and the mitochondrial UPR

Aging Cell

Antoni Pla¹  Mercedes M. Pérez‐Jiménez¹  Manuel D. Martínez‐Bueno¹  Patricia de la Cruz‐Ruiz¹  Roxani Gatsi¹  Blanca Hernando‐Rodríguez¹  Marta Artal‐Sanz¹  María Jesús Rodríguez‐Palero¹ 

[1] Andalusian Centre for Developmental Biology, Consejo Superior de Investigaciones Científicas/Junta de Andalucía/Universidad Pablo de Olavide, Seville, Spain;Department of Molecular Biology and Biochemical Engineering, Universidad Pablo de Olavide, Seville, Spain;

关键词: autophagy;    lipogenesis;    mitochondria;    prohibitin;    SGK‐1;    UPR;   

DOI  :  10.1111/acel.13359

来源: Wiley

【 授权许可】

CC BY