Loss of Fis1 impairs proteostasis during skeletal muscle aging in Drosophila

Aging Cell

Elena Ziviani¹  Sophia von Stockum¹  Yu‐Chen Tsai²  Yi‐Wen Chang³  Hsueh‐Fen Juan³  Matthew P. Su⁴  Azusa Kamikouchi⁴  Shih‐Peng Chan⁵  Jinn‐Moon Yang⁶  Horng‐Dar Wang⁷  Jian‐Chiuan Li⁸  Rei‐Wen Liu⁹  Tai‐Ting Lee^1,10  Chun‐Hong Chen^1,11  Po‐Lin Chen^1,11 

[1]Department of Biology, University of Padova, Padova, Italy

[2]Fondazione Ospedale San Camillo, IRCCS, Lido di Venezia, Venezia, Italy

[3]Department of Life Science and Life Science Center, Tunghai University, Taichung, Taiwan

[4]Department of Life Science, National Taiwan University, Taipei, Taiwan

[5]Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Japan

[6]Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan

[7]Genome and Systems Biology Degree Program, College of Life Science, National Taiwan University, Taipei, Taiwan

[8]Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan

[9]Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan

[10]National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan

[11]National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan

[12]Department of Life Science and Life Science Center, Tunghai University, Taichung, Taiwan

[13]National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan

[14]Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Japan

[15]Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan

[16]National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan

[17]National Mosquito‐Borne Diseases Control Research Center, National Health Research Institutes, Zhunan, Taiwan

关键词: aging;    Drosophila melanogaster;    Fis1;    mitochondria;   

DOI  :  10.1111/acel.13379

来源: Wiley

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