VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

Aging Cell

Jun Liu¹  Mengyue Niu²  Karina Bondelid³  Xiongwei Zhu³  Sandra L. Siedlak³  Sandy Torres³  Wenzhang Wang³  Fanpeng Zhao³  Hisashi Fujioka⁴ 

[1] Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;Department of Pathology, Case Western Reserve University, Cleveland, OH, USA;Department of Pathology, Case Western Reserve University, Cleveland, OH, USA;Electron Microscopy Core Facility, Case Western Reserve University, Cleveland, OH, USA;

关键词: mitochondria dynamics;    neurodegeneration;    Parkinson's disease;    VPS35;    α‐synuclein;   

DOI  :  10.1111/acel.13347

来源: Wiley

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