Regulatory KIR+RA+ T cells accumulate with age and are highly activated during viral respiratory disease

Aging Cell

Rimke J. Postel¹  Rob Mariman¹  Jelle de Wit¹  Vinitha Kandiah¹  Josine van Beek¹  Teun Guichelaar¹  Jeroen Hoeboer¹  Daan K. J. Pieren¹  Noortje A. M. Smits¹  Debbie van Baarle² 

[1] Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands;Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands;Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands;

关键词: aging;    CD8 T cells;    killer‐cell immunoglobulin‐like receptors;    regulatory T cells;    respiratory viral infection;    T‐cell activation;    viral respiratory disease;   

DOI  :  10.1111/acel.13372

来源: Wiley

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