Dual Treatment of Hemichorea–Hemiballismus Syndrome with Tetrabenazine and Chemodenervation

Tremor and Other Hyperkinetic Movements

article

Chizoba C. Umeh¹  Paige Nichols¹  Liana S. Rosenthal¹  Zoltan Mari¹ 

[1] Johns Hopkins Medical Center, Department of Neurology, Movement Disorders Division

关键词: Hemichorea–hemiballismus;    dystonia;    tetrabenazine;    chemodenervation;    onabotulinumtoxinA;    hyperkinetic movements;   

DOI  :  10.5334/tohm.97

学科分类：社会科学、人文和艺术（综合）

来源: Ubiquity Press

【 摘 要 】

Background: Hemichorea–hemiballismus involves unilateral involuntary flailing movements and random jerking movements involving proximal or distal muscles. We describe a case of hemichorea–hemiballismus with dystonia after stroke. Treatment with tetrabenazine and chemodenervation produced beneficial responses. Effective treatment of both hemichorea–hemiballismus and dystonia due to stroke has not been reported. Case Report: A 65-year-old male developed left hemichorea–hemiballismus and dystonia after a right hemisphere stroke. He underwent initial treatment with neuroleptics and anticonvulsants without improvement. Subsequent treatment with tetrabenazine improved the hemichorea–hemiballismus and chemodenervation reduced the dystonia. Discussion: Hemichorea–hemiballismus associated with dystonia can be improved with both tetrabenazine and chemodenervation.

【 授权许可】

CC BY