Toxicological Evaluation of Bisphenol A and Its Analogues

Turkish Journal of Pharmaceutical Sciences

article

İrem İYİGÜNDOĞDU¹  Aylin ÜSTÜNDAв  Yalçın DUYDU² 

[1] Gazi University Faculty of Pharmacy, Department of Toxicology;Ankara University Faculty of Pharmacy, Department of Toxicology

关键词: Bisphenols;    bisphenol A;    endocrine disruptor;    bisphenol S;    bisphenol F;   

DOI  :  10.4274/tjps.galenos.2019.58219

来源: Galenos Yayinevi

【 摘 要 】

Bisphenol A (BPA) is known as one of the oldest synthetic compounds with endocrine disrupting activity. It is commonly used in the production of epoxy resins, polycarbonates, dental fillings, food storage containers, baby bottles, and water containers. BPA is associated with various health problems such as obesity, diabetes, chronic respiratory diseases, cardiovascular diseases, renal diseases, behavior disorders, breast cancer, tooth development disorders, and reproductive disorders. Increasing health concerns have led the industry to seek alternatives to BPA. As BPA is now being excluded from several consumer products, the use of alternative compounds is increasing. However, the chemicals used to replace BPA are also BP analogues and may have similar or higher toxicological effects on organisms. The aim of this review is to focus on the toxicological profiles of different BP analogues (i.e. BPS and BPF) which are increasingly used today as alternative to BPA.

【 授权许可】

Unknown