Medication Safety in Patients under 18 Years Old, a Retrospective Study based on Iraqi Pharmacovigilance Center Database

Iraqi Journal of Pharmaceutical Sciences

ARTICLE

Hani Gh. Jawad¹  Eman S. Saleh²  Manal M. Younus³ 

[1] Ministry of Health and Environment, Gastroenterology and Hepatology Specialized Hospital;Department of Clinical Laboratory Science, College of Pharmacy, University of Baghdad;Iraqi Pharmacovigilance Center, Ministry of Health

关键词: Medication errors;    Adverse drug reaction;    Medication safety;    Iraqi pharmacovigilance center;    Pediatric.;   

DOI  :  10.31351/vol29iss2pp152-160

学科分类：计算机网络和通讯

来源: College of Pharmacy University of Baghdad

【 摘 要 】

Medication safety is an important part of the comprehensive patient safety term. Medication safety is gaining more attention as the World Health Organization set the goal of decreasing medication harm by (50%) for the next 5 years when launching the third global challenge. Studying medication safety in the risk groups such as young ages, children are crucial to learn more about the effect of medicines in this risk group since they are not included in the clinical trials. Adverse drug reaction is defined as any harm resulted from the drug itself during medical process journey, while medication errors are any harm resulted from the treatment process rather than the drug or it is the result of the failure in a step of the treatment process and by that it came clear that adverse drug reaction in non-preventable event while medication error is preventable one. The objectives of this study are to find the preventable medication errors from the Iraqi database of Adverse drug events in ages from neonatal to adolescent age. This study is a retrospective descriptive study conducted using the Iraqi pharmacovigilance center database. The study included reports that were received by the Iraqi pharmacovigilance center from 1st of January 2014 until the 1st of January 2020. In this study, the total number of reports included was 2344. The type of medication involved, type of adverse event, type of error and phase of error were reviewed. The results show that (50.47%) of the adverse event following administrating medication to the pediatric population were medication errors while adverse drug reaction represented the remaining (49.53%). The prescribing phase was the one of greatest error (59.43%) and the least one was dispensing (0.17%). Most reports were general skin and subcutaneous tissue. The most common type of encountered error was self-medication with the non-over-the counter drug by (44.28%). The result of the present study revealed that medication errors contribute significantly to adverse drug event among patients under 18 years old. This study highlights the importance of monitoring medication safety specifically in the risk groups.

【 授权许可】

CC BY